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. 2018 Feb 6;13(2):e0188710. doi: 10.1371/journal.pone.0188710

Table 4. Metabolites identified and compared attending the periodontal satatus.

* p < 0.05 and ** p < 0.01.



Periodontal status
Periodontally healthy Gingivitis/early periodontitis Moderate/Advanced periodontitis
Mean Standar deviation Mean Standar deviation Mean Standar deviation p-value
Caproate** .005886 .001438 .005855 .001990 .006261 .002163 .00531
Isocaprate+butyrate** .008794 .001343 .009382 .002751 .010995 .003623 .00005
Isovalerate** .005233 .001176 .005702 .001588 .006760 .002470 .00047
Isoleucine* .008548 .001283 .008509 .002108 .009497 .002249 .01187
Isopropanol+Methanol* .010647 .009113 .009472 .006538 .012522 .018816 .04489
4-Aminobutyrate* .003381 .000825 .003484 .000939 .004105 .001216 .01407
Choline* .002397 .000431 .002379 .000429 .002444 .000597 .02388
Sucrose* .005860 .001630 .005397 .001031 .004765 .001339 .02564
Sucrose+Glc+Lys* .025448 .009300 .024012 .006007 .021597 .004739 .04969
Lactate+Proline** .011513 .002817 .011886 .005237 .010010 .002031 .00536
Lactate* .002194 .000798 .002237 .001264 .001796 .000570 .02092
Proline ** .001810 .000527 .001946 .000898 .001653 .000415 .00934