Table 1. Parameters of Morris water maze.
Mice groups | Sex / Age | Platform diameter | Training | Probe | |||
---|---|---|---|---|---|---|---|
Trials /Day | Time /Trail |
Trails /Day |
Time /Trail |
||||
Test 1 | Ddb1F/F | 5 males and 3 females / 5–8 month | 10 cm | 3 | 90s | 3 | 60s |
Ddb1F/F; Camk2α-Cre | 4 males and 3 females / 5–8 month | ||||||
Test 2 | CrbnF/F | 2 males and 3 females / 7–9 month | 10 cm | 4 | 60s | 4 | 60s |
CrbnF/F; Nestin-Cre | 4 males and 5 females / 7–9 month | ||||||
Test 3 | CrbnF/F | 1 male and 7 females / 8–12 month | 12.5 cm | 4 | 90s | 4 | 90s |
CrbnF/F; Nestin-Cre | 2 males and 5 females / 9–10 month | ||||||
CrbnF/F; Nestin-Cre + BMS-204352 | 2 males and 5 females / 9–10 month |