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. 2018 Feb 6;13(2):e0192286. doi: 10.1371/journal.pone.0192286

Fig 1. Targeting strategy for LSL-TPP1 transgene.

Fig 1

CAG, chicken-actin promoter; Int, chicken actin splice donor, rabbit globin splice acceptor intron; STOP, stop cassette composed of PGK-neo / 4 x poly(A) sites / RNA polymerase pause site / linker containing stop codons in all reading frames; mTpp1, mouse TPP1 coding sequence; pA, rabbit globin poly(A) site.