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. Author manuscript; available in PMC: 2018 Feb 6.
Published in final edited form as: Adv Exp Med Biol. 2017;1042:207–228. doi: 10.1007/978-981-10-6955-0_10

Fig. 10.3.

Fig. 10.3

Comparison of the human and the yeast GINS structures. (a) Human GINS with each subunit shown in a different color (PDB 2Q9Q). An N-terminal insertion loop in Psf3 is highlighted by a semitransparent circle near the central pore region. (b) The yeast GINS structure, extracted from the CMG structure (PDB 3JC6), is shown in the same color scheme as in (a). (c) Superimposition of the human and the yeast GINS structures, revealing that the structural variation is focused in the central region. (d) Surface representation of the yeast GINS structure. The central pore is too small to thread ssDNA