Table 4.
Normal ECG, n = 25 | Abnormal ECG, n = 34 | p | |
---|---|---|---|
Gender, M/F | 16/9 | 23/11 | NS |
Age, mo | 71 ± 58 | 52 ± 53 | NS |
PICU LOS, days | 2 [0.8–9] | 2 [0.5–24] | NS |
HR, bpm | 127 ± 30 | 126 ± 30 | NS |
PR interval, ms | 121 ± 20 | 122 ± 20 | NS |
QRS interval, ms | 80 ± 46 | 80 ± 46 | NS |
QTc interval, ms | 414 ± 23 | 414 ± 23 | NS |
pH | 7.29 ± 0.03 | 7.25 ± 0.03 | NS |
pCO2, mmHg | 49 ± 3 | 53 ± 4 | NS |
HCO3, mEq/L | 22 ± 1 | 23 ± 1 | NS |
BE | −4.1 ± 0.9 | −4.7 ± 1.2 | NS |
Electrolyte abnormality | 4 (16%)a | 11 (32%)b | NS |
Serum Ca2+, mg/dL | 9.2 ± 0.2 | 9.2 ± 0.1 | NS |
Seizure duration, min | 29 ± 6c | 38 ± 8d | NS |
Number of acute AEDs | 2 [0–3] | 2 [0–3] | NS |
Fosphenytoin | 16 (64%) | 19 (56%) | NS |
Benzodiazepines | 22 (88%) | 24 (71%) | NS |
Levetiracetam | 3 (12%) | 10 (29%) | NS |
Phenobarbital | 3 (12%) | 1 (3%) | NS |
History of epilepsy | 9 (36%) | 22 (65%) | 0.04 |
Duration of epilepsy, mo | 16 [7.3–88.5]e | 16 [6.5–61]f | NS |
Generalized tonic–clonic seizures | 6/9 (67%) | 15/22 (68%) | NS |
Number of chronic AEDs | 1 [0–3] | 1 [0–5] | NS |
Values are expressed as mean ± standard error of the mean, median [min–max], or n (%).
AED, antiepileptic drug; BE, base excess; ECG, electrocardiogram; F, female; HR, heart rate; LOS, length of stay; M, male; NS, not significant; PICU, Pediatric Intensive Care Unit; QTc, corrected QT.
an = 21, bn = 29, cn = 18, dn = 31, en = 10, fn = 21.