Table 1.
Prohormones detected in extracts of ST1- and hot water-treated samples.
| Prohormone | ST1 | Hot Water |
|---|---|---|
| Cerebellin-1 | X | X |
| Chromogranin-A | X | |
| Cocaine- and amphetamine-regulated transcript protein | X | X |
| Corticoliberin | X | X |
| Neuroendocrine protein 7B2 | X | |
| Neuropeptide S | X | |
| Neurosecretory protein VGF | X | X |
| Neurotensin/neuromedin N | X | |
| Pituitary adenylate cyclase-activating polypeptide | X | X |
| Proenkephalin-A | X | X |
| Proenkephalin-B | X | |
| Progonadoliberin-1 | X | X |
| Secretogranin-1 | X | X |
| Pro-MCH | X | X |
| ProSAAS | X | X |
| Protachykinin-1 | X | X |
| Prothyroliberin | X | X |
| Secretogranin-2 | X | X |
| Secretogranin-3 | X | X |
| Somatostatin | X | X |
| Tachykinin-3 | X | |
| Vasopressin-neurophysin 2-copeptin | X |
Prohormones detected in analyte extracts of different biological replicates (N=3) for each of the sample treatment procedures were combined, with peptide duplicates removed. A prohormone was considered only if it had at least one unique full-length peptide sequence; full length is defined as a peptide that is flanked by known basic cleavage sites in the prohormone.