Table 1.
Characteristics of the Subjects
| |
PiMM |
PiZZ |
|
|---|---|---|---|
| Characteristic | (n = 5) | (n = 5) | P Value (t Test) |
| Age, yr | 38.5 (24–68) | 44 (35–55) | >0.05 |
| Male sex, n | 3 | 2 | N/A |
| FEV1% predicted | 103.1 (95.5–106) | 89.9 (58–111.9) | >0.05 |
| FEV1/FVC | 86.8 (82.0–91.0) | 71.1 (55.0–83.7) | <0.05 |
| Current smoker | No | No | N/A |
Definition of abbreviations: FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; N/A, not applicable; PiMM, individuals homozygous for normal PiM allele; PiZZ, individuals homozygous for mutant PiZ allele.