Table 8. Multivariate cox regression analysis of potential prognostic factors for survival in patients with EAC.

Variables	Multivariate analysis
	HR (95%CI)	P-value
Tumor status, T3–T4 vs. T1–T2	1.759 (1.084–2.854)	0.022
Stage, III–IV vs. I–II	2.515 (1.002–6.318)	0.050
LNM, yes vs. no	3.613(1.720–8.679)	0.876
Grade, III vs. I–II	2.791 (1.403–5.549)	0.003
Low uc.189 vs. High uc.189	0.015 (0.005–0.046)	<0.001
Tumor size (cm), ≥10 vs. <10	1.904(0.787–4.609)	0.132
Age (years), ≥60 vs. <60	1.627(0.720–3.679)	0.257

Abbreviations: HR hazard ratio, CI confidence interval, LNM lymph node metastasis ^*P < 0.05, statistically significant.