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. 2018 Jan 10;9(7):7623–7630. doi: 10.18632/oncotarget.24143

Table 4. Incidence and subhazard ratios of ischemic stroke between cancer patients with and without atrial fibrillation according to CHA2DS2-VASc score with the use of the competing-risk regression model.

Atrial fibrillation
No Yes
CHA2DS2-VASc score Event Rate# Crude SHR
(95% CI)
Adjusted SHR (95% CI) Event Rate# Crude SHR
(95% CI)
Adjusted SHR
(95% CI)
0∼1 4887 37.6 1 (Reference) 1 (Reference) 74 188.8 4.67 (3.71, 5.87)*** 4.15 (3.29, 5.23)***
2∼3 8809 120.2 1 (Reference) 1 (Reference) 440 290.1 1.98 (1.80, 2.18)*** 1.95 (1.77, 2.14)***
4∼5 3736 174.7 1 (Reference) 1 (Reference) 506 362.5 1.84 (1.67, 2.01)*** 1.86 (1.69, 2.04)***
>5 184 57.9 1 (Reference) 1 (Reference) 54 114.3 1.78 (1.32, 2.41)*** 1.82 (1.34, 2.47)***

Rate#, per 1,000 person-year; Crude SHR, crude subhazard ratio.

Adjusted for hyperlipidemia, chronic obstructive pulmonary disease, chronic kidney disease, hyperthyroidism, sleep disorder and gout; further controlling for death to estimate adjusted subhazard ratio.

***p < 0.001.