Table 4. Incidence and subhazard ratios of ischemic stroke between cancer patients with and without atrial fibrillation according to CHA2DS2-VASc score with the use of the competing-risk regression model.
Atrial fibrillation | ||||||||
---|---|---|---|---|---|---|---|---|
No | Yes | |||||||
CHA2DS2-VASc score | Event | Rate# | Crude SHR (95% CI) |
Adjusted SHR† (95% CI) | Event | Rate# | Crude SHR (95% CI) |
Adjusted SHR† (95% CI) |
0∼1 | 4887 | 37.6 | 1 (Reference) | 1 (Reference) | 74 | 188.8 | 4.67 (3.71, 5.87)*** | 4.15 (3.29, 5.23)*** |
2∼3 | 8809 | 120.2 | 1 (Reference) | 1 (Reference) | 440 | 290.1 | 1.98 (1.80, 2.18)*** | 1.95 (1.77, 2.14)*** |
4∼5 | 3736 | 174.7 | 1 (Reference) | 1 (Reference) | 506 | 362.5 | 1.84 (1.67, 2.01)*** | 1.86 (1.69, 2.04)*** |
>5 | 184 | 57.9 | 1 (Reference) | 1 (Reference) | 54 | 114.3 | 1.78 (1.32, 2.41)*** | 1.82 (1.34, 2.47)*** |
Rate#, per 1,000 person-year; Crude SHR, crude subhazard ratio.
†Adjusted for hyperlipidemia, chronic obstructive pulmonary disease, chronic kidney disease, hyperthyroidism, sleep disorder and gout; further controlling for death to estimate adjusted subhazard ratio.
***p < 0.001.