Figure 2. Correlation of MDSCs and TAMs between peripheral blood and tumor microenvironment.
(A). Representative immunochemistry image of CD68+ and S100A9+ cells in lung adenocarcinoma tissue. 200×. (B) Representative immunochemistry image of double stain of CD68 (Brown) and S100A9 (Blue) of lung adenocarcinoma. 200×. (C) Correlation between percentage of CD11b+CD14+S100A9+ MDSCs in peripheral blood and number of S100A9+ cells in tumor tissue. (D) Correlation between percentage of CD11b+CD14+S100A9+ MDSCs in peripheral blood and number of CD68+ cells in tumor tissue. (E) Representative immunochemistry image of S100A9+ cells (brown) in tumor tissue and inner lumen of blood vessels. 100× (F) Kaplain-Meier curve of PFS according to median number of S100A9+ cells in tumor tissue. Dark line: low S100A9+ cells, dashed line: high S100A9+ cells. (G) Kaplain-Meier curve of PFS according to median number of CD68+ cells in tumor tissue. Dark line: low CD68+ cells, dashed line: high CD68+ cells.