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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Ultrasound Med Biol. 2017 Dec 25;44(3):622–634. doi: 10.1016/j.ultrasmedbio.2017.11.005

Table 1.

Criterion for the intracellular delivery score (IDS) to find optimal treatment conditions.

Criterion for the intracellular delivery score (IDS) which was categorized, and calculated by the interaction of the delivery efficiency (D), cell membrane permeability (P), and cell viability (V) after 4 and 20 hours of treatment.

Delivery efficiency Permeability Viability
90% ≤ D +5 15 ≤ P +5 90% ≤ V −0
70% ≤ D < 90% +4 10 ≤ P < 15 +4 70% ≤ V < 90% −2
50% ≤ D < 70% +3 5 ≤ P < 10 +3 50% ≤ V < 70% −4
30% ≤ D < 50% +2 1 ≤ P < 5 +2 30% ≤ V < 50% −8
10% ≤ D < 30% +1 0.01 ≤ P < 1 +1 10% ≤ V < 30% −9
D < 10% +0 P < 0.01 +0 V < 10% −10