Table 3.
Uni- and multivariate Cox regression analyses of FTO rs9939609 polymorphism in recurrent VTE patients
| All patients | Male | Female | ||||||||||
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| Univariate | P | Multivariate | P* | Univariate | P | Multivariate | P* | Univariate | P | Multivariate | P* | |
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| Genotypes | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | ||||||
| rs9939609 | ||||||||||||
| TT | Reference | Reference | Reference | Reference | Reference | Reference | ||||||
| AT | 0.94 (0.63–1.41) | 0.775 | 0.86 (0.56–1.30) | 0.469 | 0.88 (0.49–1.58) | 0.674 | 0.84 (0.46–1.55) | 0.575 | 1.01 (0.58–1.77) | 0.978 | 0.89 (0.50–1.59) | 0.692 |
| AA | 1.35 (0.84–2.19) | 0.219 | 1.30 (0.80–2.13) | 0.289 | 1.90 (1.0–3.58) | 0.048 | 1.83 (0.95–3.54) | 0.072 | 0.88 (0.41–1.88) | 0.741 | 0.84 (0.39–1.79) | 0.645 |
| TT & AT | Reference | Reference | Reference | Reference | Reference | Reference | ||||||
| AA | 1.40 (0.93–2.12) | 0.111 | 1.43 (0.93–2.19) | 0.100 | 2.05 (1.20–3.49) | 0.009 | 2.03 (1.16–3.55) | 0.013 | 0.88 (0.44–1.73) | 0.701 | 0.90 (0.45–1.78) | 0.752 |
P* Adjusted for BMI, acquired risk factors, mild and severe thrombophilia, and family history of VTE.