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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Exp Mol Pathol. 2017 Nov 24;104(1):1–8. doi: 10.1016/j.yexmp.2017.11.012

Figure 3. Dysregulation of oxidative stress responses in end-stage PSC/IBD.

Figure 3

(A) Western analysis of overall expression of SOD1, SOD2, catalase, Gpx1, NQO1, HO-1, Hsp70, GSTA4, GSTμ and GSTπ. Western blots were performed as described using 10μg of whole cell extracts prepared from normal, PSC/IBD hepatic tissue. Expression was normalized against GAPDH expression (B) Overall GST activity in whole cell extracts prepared from normal and PSC/IBD patients. Data are Means+/−SEM, N=6 patients per group, *p<0.05, ***p<0.001.