Table 2.
Right and left ventricular size and function, plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and pro-collagen III (PIIINP) of 40 pediatric patients with tetralogy of Fallot (TOF) and their age-matched controls.
| Patients | Controls | P value | |
|---|---|---|---|
| Number of subjects | 40 | 43 | |
| RV EDV ml/m2 | 115 ± 26.5 | 83.6 ± 14.8 | < 0.0001 |
| RV EF (%) | 50.1 ± 8.6 | 60.0 ± 4.8 | < 0.0001 |
| Pulmonary regurgitation (%) | 28.5 ± 17.7 | 0.5 ± 2.50 | < 0.0001 |
| LV EDV ml/m2 | 75.3 ± 15.1 | 80.9 ± 13.7 | ns. |
| LV EF (%) | 61.6 ± 8.6 | 63.0 ± 4.8 | ns. |
| Aortic regurgitation (%) | 1.3 ± 2.9 | 0 | |
| NT-proBNP levels (ng/l) | 147 ± 82 | 53 ± 36 | < 0.0001 |
| Plasma PIIINP levels (μg/l) | 12.3 ± 4.9 | 9.1 ± 3.9 | 0.0009 |