Table 3.
Quantitative OCT analysis per cross-section with ISR > 50%.
| Variable |
First generation (n = 143) |
p |
Second generation (n = 89) |
p |
p* |
p** |
||
|---|---|---|---|---|---|---|---|---|
| ≤ 1 year (n = 43) | > 1 year (n = 100) | ≤ 1 year (n = 70) | > 1 year (n = 19) | |||||
| Mean stent CSA, mm2 | 5.0 ± 2.1 | 5.1 ± 1.7 | 0.88 | 8.4 ± 3.2 | 4.3 ± 1.1 | < 0.01 | < 0.01 | 0.01 |
| Mean lumen CSA, mm2 | 1.6 ± 1.3 | 1.6 ± 1.2 | 0.86 | 3.2 ± 1.3 | 1.9 ± 0.5 | < 0.01 | < 0.01 | 0.08 |
| NHI CSA, mm2 | 3.5 ± 1.0 | 3.5 ± 0.9 | 0.91 | 5.2 ± 2.4 | 2.4 ± 0.7 | < 0.01 | < 0.01 | < 0.01 |
| NIH area, % | 72.1 ± 12.1 | 71.4 ± 14.9 | 0.79 | 61.1 ± 8.4 | 55.5 ± 5.2 | < 0.01 | < 0.01 | < 0.01 |
| Restenosis length, mm | 7.1 ± 11.9 | 5.3 ± 6.7 | 0.62 | 6.4 ± 6.4 | 4.7 ± 2.5 | 0.50 | 0.86 | 0.88 |
Continuous variables are expressed as the mean ± SD. CSA: cross sectional area; NIH: neo-intimal hyperplasia. p: comparison within each DES generation; p*: comparison of early ISR between generations; p**: comparison of late ISR between generations.