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. 2018 Feb 2;9:23. doi: 10.3389/fgene.2018.00023

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Copyright © 2018 Yang, Banerjee, Cao, Bai, Peng, Chen, Huang, Han, Feng, Yi, Song and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Radiological examination of Proband and Proband’s Sister. The radiological examination of Proband (II-5), (A) CT showed situs inversus. (B) Coronal view of paranasal sinus MRI shows bilateral maxillary sinusitis and ethmoid sinusitis. (C,D) HRCT of chest shows bronchitis and bronchiolitis. Bronchiectasia involves in left lobes. Centrilobular nodules and tree-in-bud sign distribute diffusely in both lobes.The radiological examination of Proband’s sister (II-1), (E) CT showed situs inversus, (F) Transverse view of sinus MRI showed bilateral maxillary sinusitis, (G,H) HRCT of chest showed bronchitis and bronchiolitis, ring-shaped or ductal opacities bronchiectasia involves in both lobes. Secretion obstruction can be seen in some saccular bronchiectasis in the upper left lobes.