Table 1.
Effects of treatment of rats with KBrO3 separately, or in combination with gum acacia (GA), on some physiological parameters
| Parameters/Treatment | Initial body weight (g) | Final body weight (g) | Change in body wright (%) | Relative kidney weight (%) | Water intake (mL) | Urine output (mL) |
|---|---|---|---|---|---|---|
| Control | 198.17±10.7 | 244.0±8.9 | 23.93±4.09 | 0.74±0.06 | 14.08±1.64 | 7.75±0.54 |
| GA | 199.0±5.09 | 220.0±6.98 | 10.48±1.01 | 0.77±0.03 | 20.0±3.92 | 7.83±1.33 |
| KBrO3 (5 mg/Kg) | 199.83±12.06 | 249.67±5.84 | 26.5±5.45 | 0.76±0.03 | 15.42±1.5 | 7.5±0.96 |
| KBrO3 (5 mg/Kg)+GA | 199.33±8.89 | 203.3±8.47 | 2.08±0.82*,° | 0.79±0.05 | 16.58±2.48 | 7.67±0.76 |
| KBrO3 (15 mg/Kg) | 198.67±11.13 | 248.83±10.03 | 26.35±5.97 | 0.79±0.06 | 13.33±2.0 | 7.5±1.06 |
| KBrO3 (15 mg/Kg)+GA | 200.0±6.61 | 221.67±10.17 | 10.63±2.02 | 0.72±0.03 | 14.17±2.48 | 7.17±0.91 |
| KBrO3 (45 mg/Kg) | 199.0±7.87 | 241.83±3.79 | 22.32±4.3 | 0.81±0.02 | 16.92±2.29 | 7.83±1.22 |
| KBrO3 (45 mg/Kg)+GA | 199.67±11.51 | 219.17±11.44 | 10.03±2.16 | 0.83±0.05 | 11.67±1.96 | 7.5±1.11 |
| KBrO3 (135 mg/Kg) | 205.0±9.57 | 214.17±15.1 | 3.94±3.01* | 0.83±0.01 | 27.0±4.28* | 18.33±2.22* |
| KBrO3 (135 mg/Kg)+GA | 203.5±12.04 | 193.67±15.35* | 5.18±3.06* | 0.69±0.02 | 11.0±1.06° | 5.17±1.01° |
Values in the table are means ± SEM (n = 6). Different doses of KBrO3 were orally administered (in distilled water) for 28 days, and GA (15%W/V) was given concomitantly in the drinking water. On the 28th day of treatment, the rats were placed in metabolic cage to collect urine.
*
denote significance of different groups vs. control;
°
denote significance of groups treated with KBrO3 alone vs. it correspondence groups treated with GA.