Definitions, patients’ distribution, and stage migrations in AJCC 7th and AJCC 8th TNM staging systems. A: AJCC 7th TNM staging system. B: AJCC 8th TNM staging system. According to the definition, there were no changes in stage IA, IB, IIA, and IV from AJCC 7th staging system to 8th staging system. Stage migrations were occurred in subgroups highlighted in the blue dashed rectangle, including stage IIB, IIIA, IIIB, and IIIC. Exact patients number was also shown. On the whole, the percentage of patients with stage IIIA, IIIB, and IIIC was 15.6%, 21.7%, and 21.5% in AJCC 7th staging system, and changed to 34.3%, 16.5%, and 8.0% in AJCC 8th staging system, respectively. Purple-framed categories were upstaged GC cases. Blue-framed categories were downstaged GC cases. Green-framed categories were unchanged GC cases.