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. 2018 Feb 2;9:150. doi: 10.3389/fimmu.2018.00150

Figure 6.

Figure 6

Killer immunoglobulin-like receptor (KIR) expression is enriched in NKG2A- natural killer (NK) cells. (A) Day 12 expanded CD56bright NK cells were gated on NKG2A expression. (B) NKG2A+ (top) and NKG2A− (bottom) cells were interrogated for their expression of both KIR2DL1/DS1 and KIR3DL1/DS1 (left). KIR2DL2/DL3/DS2 expression was examined on the double positive cells (right). (C) Percent of total NKG2A+ or NKG2A− cells that are positive for all three KIRs. Statistical significance was assessed by Student’s t-test. (D) Day 0 CD56dim NK cells were gated on NKG2A expression. (E) NKG2A+ (top) and NKG2A− (bottom) cells were interrogated for their expression of both KIR2DL1/DS1 and KIR3DL1/DS1 (left). KIR2DL2/DL3/DS2 expression was examined on the double positive cells (right). (F) Percent of total NKG2A+ or NKG2A− cells that are positive for all three KIRs. Statistical significance was assessed by Student’s t-test (*p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001).