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. 2018 Feb 2;9:16. doi: 10.3389/fpsyt.2018.00016

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Copyright © 2018 Pu, Nakagome, Itakura, Ohtachi, Iwata, Nagata and Kaneko.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of cognitive insight on subjective quality of life (QOL) through right frontotemporal function. Path C represents the variance in the level of cognitive insight that is associated with the subjective QOL ((A) vitality or (B) mental health) level, and Path C′ represents the association between the level of cognitive insight and subjective QOL after taking into account right frontotemporal function as a mediator. When right frontotemporal function was included in the model, the direct effect of cognitive insight (self-reflectiveness) on subjective QOL (dashed line) (left: vitality, right: mental health) was no longer significant, indicating a fully mediated effect. Path AB is the mediation effect and is significant at p < 0.05 based on confidence intervals from bias-corrected bootstrapping of 5,000 samples.