Table 2.
Correlations between the VFT-related hemodynamic responses and measures of cognitive insight and subjective QOL in patients with schizophrenia.
| Cognitive insight |
Region 1 (DLPFC/FPC) | Left region 2 (left VLPFC/aTC) | Right region 2 (right VLPFC/aTC) | ||
|---|---|---|---|---|---|
| Self-reflectiveness | Self-certainty | ||||
| Frontotemporal region | |||||
| Region 1 (DLPFC/FPC) | 0.337 | −0.100 | – | – | – |
| Left region 2 (left VLPFC/aTC) | 0.273 | 0.011 | – | – | – |
| Right region 2 (right VLPFC/aTC) | 0.506*** | −0.163 | – | – | – |
| Subjective QOL | |||||
| Physical functioning | −0.171 | 0.079 | 0.128 | 0.135 | 0.060 |
| Role limitations—physical | 0.043 | −0.075 | 0.050 | 0.072 | 0.188 |
| Bodily pain | 0.020 | −0.312 | 0.117 | 0.239 | 0.232 |
| General health | 0.121 | −0.241 | 0.287 | 0.392* | 0.378 |
| Vitality | 0.411* | −0.057 | 0.495*** | 0.492* | 0.501*** |
| Social functioning | 0.226 | −0.082 | 0.301 | 0.222 | 0.120 |
| Role limitations—emotional | 0.183 | −0.094 | 0.213 | 0.168 | 0.080 |
| Mental health | 0.508*** | −0.047 | 0.320 | 0.461** | 0.509*** |
VFT, verbal fluency task; QOL, quality of life; DLPFC/FPC, dorsolateral prefrontal cortex and frontopolar cortex; VLPFC/aTC, ventrolateral prefrontal cortex and the anterior part of the temporal cortex.
*p < 0.05.
**p < 0.01.
***p < 0.005.