Figure EV4. Degranulation of RASGRP1‐deficient CD8⁺ T and NK cells.

1. Representative dot plots showing the cell‐surface expression of CD107a/b on gated CD8⁺ T‐cell blasts of a healthy control (Ctr.) and P1.1 (Pat.) that have been stimulated for 3 h with incremental doses of coated anti‐CD3 antibody or PMA+ionomycin. One representative of three independent experiments.
2. Representative dot plots showing the cell‐surface expression of CD107a/b on gated NKp46⁺CD3⁻ cells corresponding to NK cells or CD3⁺ cells of a healthy control (Ctr.) and P1.1 (Pat.) that have been stimulated for 3 h in the presence or not of K562 target cells. One representative of two independent experiments.