Fig. 2.

Torque measurements in dosed and control mice before and after LSI. Contractile torque was determined from control (n = 13), ibuprofen-treated (n = 11), and ISDN-treated (n = 12) mice, as well as from mice treated with both drugs (Ibu + ISDN, n = 13). (A) Initial torque levels are not affected by drug dosing. (B) Torque immediately following injury on day 0 shows no effect of the drugs. (C) Torque measured on day 3 indicates no beneficial effect of the drugs in these grouped data. (D) Torque levels from day 0 postinjury and day 3 are directly compared. None of the differences are significant at P < 0.05. Data are means ± S.D.