Skip to main content
. Author manuscript; available in PMC: 2018 Feb 7.
Published in final edited form as: J Pediatr. 2013 Jul;163(1 Suppl):S25–S31. doi: 10.1016/j.jpeds.2013.03.027

Table VI.

Frequency* of clinical symptoms, prior use of antibiotics, and disease sequelae for suspected, probable, and confirmed cases ≤5 years old

Case definition Suspected
N = 16 811
Probable
N = 13 125
Confirmed cases meeting
probable case definition
N = 921
Confirmed cases that did not
meet probable case definition
N = 104
Clinical presentations: signs and symptoms
  Fever 86% 89% 90% 83%
  Headache 11% 12% 17% 9%
  Neck rigidity 23% 26% 36% 13%
  Vomiting 41% 40% 51% 39%
  Skin rash 3% 3% 4% 4%
  Petechiae 2% 2% 5% 3%
  Seizures/convulsions 68% 69% 59% 65%
  Altered consciousness 26% 26% 31% 28%
  Bulging fontanelle 14% 15% 23% 14%
  Coma 8% 7% 8% 6%
Antibiotics received prior to lumbar puncture 30% 24% 27% 43%
Disease sequelae
  Outcome (death) 3% 3% 9% 3%
  Neurologic complications (any) 75% 75% 54% 77%
*

Proportion of cases with a given symptom. Cases with missing responses are excluded.

Includes cases that did not meet probable case definition because fever was absent at presentation or the presence of fever was unknown.