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. 2018 Feb 2;8:18. doi: 10.3389/fcimb.2018.00018

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Copyright © 2018 Suligoy, Lattar, Noto Llana, González, Alvarez, Robinson, Gómez, Buzzola and Sordelli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CFU/tibia (upper) and OI (middle) from rats infected with strains HU-85a and HU-85c. Bacterial loads and OI were measured 14 weeks after intratibial challenge. The sample size was n = 9 (HU-85a) and n = 12 (HU-85c), in both panels. The scattergram bars in the upper and middle panels represent the medians. The levels of significance are shown on the charts (Mann-Whitney test). The lower panel shows the correlation of the CFU/bone counts and the OI of all the rats included in the experiments shown in the upper and middle panels (experiment quality control).