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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Child Adolesc Psychiatr Clin N Am. 2017 Jul;26(3):539–554. doi: 10.1016/j.chc.2017.03.001
Medications By Class Target Behaviors Adverse Effects Monitoring
Typical Antipsychotics (e.g haloperidol, chlorpromazine) Agitation, aggression, hyperactivity, self-injury Extrapyramidal symptoms, tardive dyskinesia AIMS
Atypical Antipsychotics (e.g risperidone, aripiprazole, olanzapine) Irritability, aggressiveness, hyperactivity, self- injurious behavior, repetitive behaviors Weight gain, somnolence, increased risk of diabetes, extrapyramidal symptoms, akathisia, tardive dyskinesia Blood glucose, HbA1C, lipids AIMS
Mood Stabilizers (e.g., lithium, valproic acid, carbamazepine) Mood lability, aggression, impulsivity, self-injurious behavior Lithium: tremor, renal and thyroid toxicity, Valproate: tremor, sedation, weight gain Carbamazepine: nausea, vomiting Renal and thyroid monitoring for lithium, liver function tests, CBC, and ammonia with valproic acid, regular drug levels for all three
SSRIs (e.g fluoxetine, sertraline, fluvoxamine) Depressed mood, anxiety, self-injurious behavior, repetitive behaviors Activation, agitation, aggression, nausea None specific
Stimulants (e.g methylphenidate) Hyperactivity, inattention, impulsivity Loss of appetite, insomnia, depressed mood Height, weight, vital signs
Alpha-agonists (e.g. clonidine, guanfacine) Hyperactivity, inattention, impulsivity, tics Hypotension, sedation, increased depression Vital signs