Table 2.
Sensitivity, Specificity, Positive Predictive Value, and Negative Predictive Value for Adolescent Reward-Related Delta Predicting First-Onset Depressive Disorder at the 18-Month Follow-Up Assessment
| Area Under the Curve | Cutoff | SEN | SPEC | PPV | NPV |
|---|---|---|---|---|---|
| .60 | +2.0 SD | 12.5 | 96.0 | 23.6 | 91.7 |
| +1.5 SD | 17.5 | 91.8 | 17.4 | 91.8 | |
| +1.0 SD | 32.5 | 84.4 | 17.1 | 92.7 | |
| +0.5 SD | 42.5 | 75.2 | 14.5 | 93.0 |
Note. The reward-related delta was multiplied by −1 to produce the inverse relationship, such that more positive values indicated a reduced neural response to rewards. The table includes sensitivity, specificity, and positive and negative predictive values for a range of cut-offs for adolescent reward-related delta. PPV = positive predictive value; NPV = negative predictive value; SD = standard deviation; SEN = sensitivity, SPEC = specificity.