Table 3.
Summary of large spearman’s rho (rs) correlations (> .5) between clinical change and microbial or lactate change variables in males
| Microbial count and lactate change | Clinical change | r s | p | n | Direction of change in bacteria associated with clinical improvement |
|---|---|---|---|---|---|
| Bacteroides | Sleep quality—PSQI | − .758 | .011 | 10 | Increase |
| General fatigue—MFI | − .738 | .004 | 13 | Increase | |
| Stress—DASS | − .701 | .011 | 12 | Increase | |
| Total symptoms—SSH | − .600 | .067 | 10 | Increase | |
| Mood disturbance—POMS total | − .573 | .066 | 11 | Increase | |
| Actigraphy wake after sleep onset | − .529 | .043 | 15 | Increase | |
| Planning—SWM—strategy | .588 | .017 | 16 | Decrease | |
| Bifidobacterium | Sleep quality—PSQI | − .681 | .030 | 10 | Increase |
| General fatigue—MFI | − .602 | .030 | 13 | Increase | |
| Anxiety—DASS | − .567 | .043 | 13 | Increase | |
| Visual learning—PAL—total errors | − .529 | .035 | 16 | Increase | |
| Clostridium | Total symptoms—SSH | .582 | .078 | 10 | Decrease |
| Verbal fluency—COWAT corrected scorea | .550 | .027 | 16 | Decrease | |
| Story memory—LM immediatea | .522 | .038 | 16 | Decrease | |
| Processing speed—RVP mean latency | .507 | .045 | 16 | Decrease | |
| Enterococcus | General fatigue—MFI | − .516 | .071 | 13 | Increase |
| Lactobacillus | Actigraphy sleep onset latency | .610 | .016 | 15 | Decrease |
| Attention—RVP A′a | − .571 | .021 | 16 | Increase | |
| Actigraphy sleep efficiencya | .512 | .051 | 15 | Decrease | |
| Streptococcus | Diary sleep onset latency | − .656 | .006 | 16 | Increase |
| d:l Lactate ratio | Actigraphy sleep onset latency | .802 | .001 | 14 | Decrease |
| Total symptoms—SSH | .567 | .112 | 9 | Decrease | |
| General fatigue—MFI | .532 | .061 | 13 | Decrease | |
| Mood disturbance—POMS total | .509 | .110 | 11 | Decrease |
N.B. Lower scores on clinical outcomes = improvement
aVariables with reversed correlations (i.e., multiplied by − 1) to allow for consistent interpretation