Table 2.
Summary of PK parameters (AUC(0-t) and Cmax) in plasma by treatment
| Variable | Salbutamol Treatment | N | Geo. Mean | CV% Geo Mean | CI 95% Lower GEO Mean | CI 95% Upper GEO Mean |
|---|---|---|---|---|---|---|
| AUC(0-t) pg.h/mL | 1.5 μm (50 μg) | 8 | 773.36 | 38.62 | 566.23 | 1056.26 |
| 6 μm (50 μg) | 8 | 1043.94 | 35.65 | 781.77 | 1394.03 | |
| Neb (2.5 mg) | 8 | 4657.29 | 53.95 | 3052.22 | 7106.41 | |
| pMDI (400 μg) | 9 | 1974.04 | 49.6 | 1376.59 | 2830.78 | |
| Cmax pg/mL | 1.5 μm (50 μg) | 8 | 335.94 | 41.54 | 240.65 | 468.96 |
| 6 μm (50 μg) | 8 | 326.47 | 39.88 | 236.79 | 450.1 | |
| Neb (2.5 mg) | 8 | 1605.95 | 74.91 | 919.19 | 2805.81 | |
| pMDI (400 μg) | 9 | 794.53 | 34.42 | 614.34 | 1027.57 |