Fig. 3.

a-e Body weight and % of total body fat in each group. Body weight measured once a week, percent adiposity was measured by MRI every two weeks. a Group 1 high-fat diet (HFD), b Group 2 (HFD+ caloric restriction (CR)), c Group 3 (HFD + CR+ curcumin (Cur)), d Group 4 (HFD + CR+ piperine (Pip)), e Group 5 (HFD + CR + Cur + Pip). Data were expressed as mean values. f Comparison of total percent body fat (area under the curve (AUC)) of each groups measured during the phase 3 (20% CR, n = 9–10). *P < 0.05 compared to Group 1 by Dunn’s multiple comparisons test. Data were expressed as mean ± standard deviations (SD)