Table 2.
Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Age (per year) | 1.048 | 1.021–1.076 | < 0.001 | 0.995 | 0.967–1.024 | 0.732 |
Male sex | 2.286 | 1.315–3.972 | 0.003 | 1.646 | 0.884–3.064 | 0.116 |
Currently smoking | 1.520 | 0.889–2.600 | 0.126 | |||
Hypertension | 2.548 | 1.457–4.456 | 0.001 | 1.121 | 0.586–2.142 | 0.730 |
Diabetes mellitus | 2.275 | 1.260–4.107 | 0.006 | 1.578 | 0.785–3.174 | 0.201 |
Body mass index > 23 (kg/m2) | 0.966 | 0.557–1.673 | 0.900 | |||
Triglycerides > 1.7 (mmol/L) | 1.260 | 0.737–2.154 | 0.398 | |||
Total cholesterol > 5.2 (mmol/L) | 1.123 | 0.585–2.153 | 0.728 | |||
LDL cholesterol > 2.6 (mmol/L) | 1.481 | 0.845–2.599 | 0.170 | |||
HDL cholesterol < 1.02 (mmol/L) | 1.909 | 1.044–3.490 | 0.036 | 1.633 | 0.834–3.197 | 0.153 |
Creatinine > 115 (μmol/L) | 1.992 | 0.622–6.378 | 0.246 | |||
C-reactive protein > 2.0 (mg/L) | 1.084 | 0.600–1.960 | 0.789 | |||
vWF > median (IU/dl) | 5.444 | 3.062–9.683 | < 0.001 | 2.686 | 1.424–5.066 | 0.002 |
BDNF < median (pg/ml) | 7.486 | 4.077–13.745 | < 0.001 | 2.590 | 1.287–5.215 | 0.008 |
CAD coronary artery disease, LDL low-density lipoprotein, HDL high-density lipoprotein, vWF von Willebrand factor, BDNF brain-derived neurotrophic factor