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. 2018 Jan 10;39(3):1003–1010. doi: 10.3892/or.2018.6205

Table I.

Enriched functions for the target genes of the upregulated miRNAs.

GO terms P-value FDR
Biological process (BP)
  GO:0006366, transcription from RNA polymerase II promoter P<0.001 P<0.001
  GO:0009790, embryo development P<0.001 P<0.001
  GO:0010628, positive regulation of gene expression P<0.001 P<0.001
  GO:0045893, positive regulation of transcription, DNA-templated P<0.001 P<0.001
  GO:1903508, positive regulation of nucleic acid-templated transcription P<0.001 P<0.001
Cellular component (CC)
  GO:0031410, cytoplasmic vesicle 2.354E-14 1.407E-11
  GO:0097708, intracellular vesicle 2.731E-14 1.407E-11
  GO:0098588, bounding membrane of organelle 1.391E-13 4.776E-11
  GO:0030054, cell junction 3.435E-13 8.845E-11
  GO:0097458, neuron part 4.348E-13 8.956E-11
Molecular function (MF)
  GO:0000981, RNA polymerase II transcription factor activity, sequence-specific DNA binding P<0.001 P<0.001
  GO:0000982, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding 1.199E-14 1.096E-11
  GO:0001228, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding 4.663E-14 2.841E-11
  GO:0019899, enzyme binding 1.765E-13 8.067E-11
  GO:0044212, transcription regulatory region DNA binding 5.079E-13 1.654E-10

GO, Gene Ontology; FDR, false discovery rate.