Table IV.

Univariate and multivariate analysis of risk factors associated with overall survival of HCC patients.

		Overall survival
Category	Subcategory	Univariate analysis	HR (95%)	Multivariate analysis	HR (95%)
Sex	Male	0.037	1.037–3.221	NA	NA
	Female
Age	<60	0.927	NA	NA	NA
	≥60
HBs-Ag	Negative	0.252	NA	NA	NA
	Positive
AFP (ng/ml)	<200	0.008	1.122–2.118	NA	NA
	≥200
Tumor size (cm)	<5	<0.001	1.703–3.446	<0.001	1.324–2.941
	≥5
Tumor no.	Single	<0.001	0.332–0.622	0.009	0.462–0.896
	Multiple
Liver cirrhosis	Absent	0.375	NA	NA	NA
	Present
Capsulation	Capsulated	<0.001	0.367–0.678	0.034	0.479–0.971
	Non-capsulated
Vascular invasion	Absent	<0.001	2.160–4.315	0.002	1.095–2.076
	Present
Edmondson grade	I–II	0.004	1.174–2.310	NA	NA
	III–IV
ELMO1	Lower expression	0.039	1.017–1.897	0.012	0.457–0.835
	Higher expression

p<0.05 is highlighted as bold text.