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. 2018 Jan 8;39(3):1090–1098. doi: 10.3892/or.2018.6199

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Copyright: © Gong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — miR-873 inhibits proliferation of CRC cells. (A and D) The expression of miR-873 in HCT116 and SW480 cells transfected with (A) miR-873 mimic (miR-873) or (D) miR-873 inhibitor (miR-873-in) as assessed by qPCR. (B and E) The effects of miR-873 overexpression on the growth of CRC cells HCT116 and SW480. MTT assays revealed that (B) miR-873 reduced cell proliferation, whereas (E) miR-873 inhibitor-transfected HCT116 and SW480 cells proliferated more rapidly than the control cells. (C and F) Representative images (left) and quantification (right) of colonies for the indicated cells, as determined by a colony formation assay. *P<0.05. CRC, colorectal cancer; qPCR, quantitative PCR.