Fig. 2.

Structure subunits, subcellular localization and gene ontology analysis of NAD⁺-dependent IDH enzyme (EC 1.1.1.41). (A) It is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. All the subunits have similar molecular masses and amino acid sequences. The IDH α subunit appears to possess the enzymatic catalytic activity [Data source: Biocyc14 databases: http://biocyc.org/META]. (B) The evidence confidence is color coded, ranging from low confidence (light green) to higher confidence (dark green). Absence of localization evidence is indicated by white color (Data source: Compartment web server: http://compartments.jensenlab.org/). (C) Gene ontology analysis of IDH enzyme [Data from: NextProt beta (http://www.nextprot.org) and GeneCards human gene database (http://www.genecards.org/)].