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. 2018 Feb 7;25:10. doi: 10.1186/s12929-018-0405-9

Fig. 3.

Fig. 3

Expressions of miR-365, β-arrestin2, ERK and CREB mRNA of rats in spinal cord tissues in each group after administration at day 7. Note: N = 8; *, P < 0.05 compared with the control group; #, P < 0.05 compared with the morphine tolerance group; ERK, extracellular signal-regulated kinase; CREB, cAMP-response element binding protein; NC, negative control