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. 2017 Dec 20;17(3):3921–3927. doi: 10.3892/mmr.2017.8333

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — (A) Relative mRNA expression levels of CYLD were increased in the CYLD overexpression group compared with in the control groups. (B and C) Antineoplastic effects of CYLD overexpression. Cell proliferation was inhibited by overexpression of CYLD in HCC827 and Calu-3 cells. (D and E) Caspase activity was significantly increased by CYLD overexpression within HCC827 and Calu-3 cells. *P<0.05 vs. blank group. CYLD, lysine 63 deubiquitinase; miR, microRNA; NC, negative control; OD, optical density.