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. 2018 Jan 16;17(3):4229–4236. doi: 10.3892/mmr.2018.8437

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Sevoflurane anesthesia induced spatial memory impairment in rats. (A) Latency time to locate the hidden platform following sevoflurane anesthesia. (B) Number of platform crossings in the probe trial tests. (C) Swimming speed of rats when locating the hidden platform. (D) Neuroapoptosis rate of the hippocampal tissues with or without sevoflurane treatment was determined by TUNEL analysis. Scale bar, 30 µm. Data are presented as the mean ± standard deviation, n=8. ***P<0.001 vs. control group. TUNEL, terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling; ns, not significant.