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mRNA expression level changes of endplate chondrocytes between cells in the central and peripheral groups following mechanical stimulation. The mRNA expression levels of chondrocyte-related genes (A) SOX9, (B) COL2A1, (C) ACAN and (D) MMP13 were not significantly different between the two groups at days 1, 3 and 7. ACAN, aggrecan; COL2A1, collagen type II α1; ICMT, intermittent cyclic mechanical tension; MMP13, matrix metalloproteinase 13; NC, negative control; SOX9, SRY-box 9.
