Table II.
Top 10 differentially expressed genes associated with hypertensive nephrosclerosis.
| Gene symbol | Gene description | Fold-change | P-value | False discovery rate |
|---|---|---|---|---|
| ALB | Albumin | 9.74 | 1.42×10−3 | 1.24×10−3 |
| DDX3Y | DEAD-box helicase 3, Y-linked | −9.14 | 2.18×10−2 | 2.11×10−2 |
| EGR1 | Early growth response 1 | 6.78 | 4.60×10−5 | 0 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 6.06 | 1.90×10−4 | 0 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 6.04 | 3.95×10−3 | 1.83×10−3 |
| RPS4Y1 | Ribosomal protein S4, Y-linked 1 | −5.92 | 3.23×10−2 | 3.17×10−2 |
| ABP1 | Amiloride binding protein 1 (amine oxidase (copper-containing)) | 5.62 | 8.38×10−3 | 5.04×10−3 |
| CYP4A11 | Cytochrome P450, family 4, subfamily A, polypeptide 11 | 5.48 | 2.18×10−3 | 1.24×10−3 |
| ALDOB | Aldolase B, fructose-bisphosphate | 5.37 | 7.44×10−3 | 5.04×10−3 |
| BBOX1 | γ-butyrobetaine hydroxylase 1 | 5.05 | 4.00×10−3 | 3.23×10−3 |