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. 2018 Jan 9;17(3):4440–4448. doi: 10.3892/mmr.2018.8405

Table III.

Top 10 significant gene ontology terms of differentially expressed genes associated with hypertensive nephrosclerosis.

Gene ontology name Differentially expressed genes P-value False discovery rate
Small molecule metabolic process 76 1.10×10−37 2.14×10−34
Cellular nitrogen compound metabolic process 21 6.42×10−17 6.25×10−14
Transmembrane transport 30 4.48×10−15 2.91×10−12
Xenobiotic metabolic process 16 2.80×10−13 1.36×10−10
Response to drug 20 1.72×10−12 6.71×10−10
Cellular response to calcium ion 9 7.68×10−12 2.49×10−9
Platelet degranulation 12 1.68×10−11 4.67×10−9
Platelet activation 16 1.16×10−10 2.82×10−8
Steroid metabolic process 10 1.36×10−10 2.95×10−8
Gluconeogenesis 9 3.41×10−10 6.64×10−8