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. 2018 Jan 9;17(3):4440–4448. doi: 10.3892/mmr.2018.8405

Table V.

Top 10 key pathways according to the degree.

Pathway name Out degree In degree Total degree
Tricarboxylic acid cycle 6 13 19
Glycolysis/gluconeogenesis 4 12 16
MAPK signaling pathway 0 16 16
Pyruvate metabolism 7 8 15
Pathways in cancer 12 0 12
Propanoate metabolism 6 5 11
Cell adhesion molecules 4 7 11
T cell receptor signaling pathway 3 8 11
Ascorbate and aldarate metabolism 4 4 8
Synthesis and degradation of ketone bodies 4 4 8

Out degree, number of downstream pathways; In degree, number of upstream pathways; Total degree, sum of out degree and in degree values.