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. 2018 Jan 9;17(3):4440–4448. doi: 10.3892/mmr.2018.8405

Table VI.

Top 10 key genes according to the degree value.

Gene Description Degree
SORD Sorbitol dehydrogenase 22
GLYAT Glycine-N-acyltransferase 21
CUBN Cubilin (intrinsic factor-cobalamin receptor) 15
PIPOX Pipecolic acid oxidase 14
UPB1 Ureidopropionase, β 14
HPD 4-hydroxyphenylpyruvate dioxygenase 14
DPYS Dihydropyrimidinase 14
SLC7A9 Solute carrier family 7 member 9 14
KMO Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 13
SHMT1 Serine hydroxymethyltransferase 1 (soluble) 13

Degree, number of the associated gene interactions with the key gene in the network.