Table 1. Domain ontology with constraints.

DomainConcept	Type	DomainConstraint
Patient
Birth_date	Date	Birth_date <= today
Death_date	Date	If death_date is not null then death_date ≥ birth_date
Hospital admission
Admission_date	Date	Discharge_date − admission_date < 1,000 d
Admission_type	Code
Discharge_date	Date	Admission_date ≤ discharge_date
Procedure
Procedure_concept_code	Code
Procedure_date	Date	Procedure_date ≥ admission_date
Medication
Medication_concept_code	Code
Medication_end_date	Date	Medication_start_date < medication_end_date
Medication_start_date	Date	Medication_start_date ≥ birth_date
Catheter intervention
Catheter_duration	Numeric	Catheter_duration ≥ 0 d Catheter_duration < 1,000 d
Catheter_insertion_date	Date	If catheter_insertion_date is not null then catheter_inserted_by is not null If catheter_insertion_date is not null and catheter_removal_date is null then catheter_rationale_for_continued_use is not null
Catheter_removal_date	Date	If catheter_removal_date is not null then catheter_insertion_date is not null
Catheter_rationale_for_continued_use	String	If catheter_rationale_for_continued_use is not null then catheter_insertion_date is not null
Catheter_inserted_by	String	If catheter_inserted_by is not null then catheter_insertion_date is not null