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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2017 Sep 26;13(1):100–112. doi: 10.1007/s11481-017-9766-1

Fig. 3.

Fig. 3

MMCP-6 -induces CCL2 release from Wt mouse glia/neurons. (A) Wt mouse glia/neurons were incubated with MMCP-6 for dose-response (5 to 200 ng/ml) and time-course studies (6 to 48 h), and CCL2 levels in the culture media were determined by ELISA (n=3). MMCP-6 induced significant CCL2 release from 6 h (at 25 ng/ml concentration) onwards from glia/neurons. Results were presented as mean ± SEM (*p<0.05 control vs MMCP-6 treated cells, One-way ANOVA and Tukey-Kramer post hoc). (B) Wt glia/neurons were incubated with MMCP-7 (100 ng/ml) for 24 h and CCL2 release was measured by ELISA (n=5). MMCP-7 induced significant CCL2 release from glia/neurons as compared to untreated control cells (*p<0.05 control vs cells incubated with MMCP-7, t-test).