Fig. 5.
MMCP-6 and MMCP-7-induce CCL2 release from Wt mouse astrocytes. Wt mouse astrocytes were grown and stimulated with MMCP-6 and MMCP-7 for 6 h and 24 h, and CCL2 release was measured in the culture media by ELISA (n=3–8). Both (A) MMCP-6 and (B) MMCP-7 induced CCL2 release in a dose-dependent manner from mouse astrocytes when compared with non-treated control cells. Results were presented as mean ± SEM (*p<0.05 control vs MMCP-6 or MMCP-7 treated cells, One-way ANOVA and Tukey-Kramer post hoc).