Table 1.
Characteristics of the CLL patients according to MYD88 mutation status
| All (n = 284) | MYD88 wild type (n = 259) | MYD88 mutated (n = 25) | |||||
|---|---|---|---|---|---|---|---|
| Characteristic | n* | % | n* | % | n* | % | P |
| Age, y (range) | 60 (54–69) | 60 (54–69) | 60 (54–66) | 0.512 | |||
| Male | 183 | 64.4 | 164 | 63.3 | 19 | 76.0 | 0.275 |
| Binet C | 86 | 32.1 | 77 | 31.3 | 9 | 40.9 | 0.351 |
| IGHV mutated | 165 | 59.1 | 143 | 56.3 | 22 | 88.0 | 0.002 |
| CD38 ≥ 30% | 52 | 18.8 | 52 | 20.6 | 0 | 0.0 | 0.011 |
| ZAP70 ≥ 20% | 71 | 28.7 | 66 | 29.1 | 5 | 25.0 | 0.802 |
| TP53 disruption | 62 | 22.5 | 58 | 23.0 | 4 | 16.7 | 0.613 |
| HBV ( + ) | 62 | 21.9 | 54 | 20.8 | 8 | 33.3 | 0.195 |
| + 12 | 42 | 18.0 | 40 | 18.9 | 2 | 9.5 | 0.383 |
| ATM deletion | 37 | 17.1 | 30 | 15.2 | 7 | 36.8 | 0.026 |
| NOTCH1 | 17 | 7.5 | 17 | 8.1 | 0 | 0.0 | 0.373 |
*Median and 25th–75th percentiles are reported for continuous variables