Table 3.
Results of hierarchical regression models with CRHR1 TAT haplotype count predicting cognitive performance on the California Verbal Learning Test-2nd Edition (CVLT-II), controlling for participant age, sex, diagnostic group (major depressive disorder with vs. without psychotic features), and evening cortisol levels
| CVLT-II variable | Full model: age, sex, diagnostic group, cortisol, and TAT haplotype count | Step 1: age, sex, diagnostic group, and cortisol | Step 2: TAT haplotype count | Significant predictors in full model |
|---|---|---|---|---|
| Total learning over trials 1–5 | R2 = 34.6% | R2 = 20.5% | ΔR2 = 14.1% | Age t = −3.33, p = .002 |
| F(5, 49) = 5.19, | F(4, 50) = 3.23, | F(1, 49) = 10.55, | TAT t = −3.25, p = .002 | |
| p = .001 | p = .020 | p = .002 | ||
| Short-delay, free recall | R2 = 30.6%, | R2 = 16.6%, | ΔR2 = 14.0%, | Group t = 2.15, p = .037 |
| F(5, 49) = 4.32, | F(4, 50) = 2.49, | F(1, 49) = 9.91, | TAT t = −3.18, p = .003 | |
| p = .002 | p = .055 | p = .003 | ||
| Long-delay, free recall | R2 = 27.2%, | R2 = 17.5%, | ΔR2 = 9.7%, | Group t = 2.62, p = .012 |
| F(5, 49) = 3.66, | F(4, 50) = 2.66, | F(1, 49) = 6.52, | TAT t = −2.55, p = .014 | |
| p = .007 | p = .043 | p = .014 |
Full model statistics and R2 are given for each step; N = 55 included in analysis