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. 2017 Nov 30;7:1261. doi: 10.1038/s41398-017-0011-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Psychostimulant-induced behavioral alterations in Df(h1q21)/+ mice. a Horizontal activity following amphetamine (AMPH) treatment (0–5 mg/kg). Genotype × treatment interaction, F_3,88 = 11.15, p < 0.001, n = 11–12/group. For full time curve see Supplementary Fig. S3A. b Horizontal activity following phencyclidine (PCP) treatment (0–5 mg/kg). n = 12/group. No significant differences between genotypes. For full time curve see Supplementary Fig. S3B. c Prepulse inhibition (PPI) following AMPH treatment. Effect of genotype, F _1,64 = 4.50, p < 0.05, n = 11–12/group. d Prepulse inhibition (PPI) following PCP treatment. Effect of genotype, F _1,61 = 12.05, n = 10–12/group. Data sets were analyzed by two-way ANOVA with post hoc comparisons using Bonferroni correction where appropriate. Stars in the upper right corner of figures represent main effect of genotype, while stars above columns represent Bonferroni-corrected post hoc tests. Data presented as means ± SEM. ^* p < 0.05; ^*** p < 0.001 vs. wild types. Dotted lines in c, d symbolize exclusion of vehicle-treated animals from statistical analyses (see Results section)