Table 1.

Breakdown of haplotype status by diagnostic group

	TTGA “risk” haplotype		CGAC “protective” haplotype		Total
Number of haplotype copies	0	1+ (2)	0	1+ (2)
Case	115	166 (36)	207	74 (9)	281
Control	64	108 (17)	127	45 (5)	172
Total	179	274 (53)	334	119 (14)	453

Subjects with 0 copies of the “risk” or “protective” haplotypes have one of seven other haplotypes on both chromosomes, namely, TGAC, TGAA, TTAC, CGAA, CTGA, TGGA, or TTGC. Subjects with 1+ copies represent subjects with one or more copies of the relevant haplotype, and homozygotes for each haplotype (2 copies) shown in parentheses. Subjects with one copy of the relevant haplotype may have any other haplotype on the alternate chromosome, including subjects who have one copy of both risk and protective haplotypes (n = 26 cases, 21 controls)